In April 2025, our Nature Genetics Perspective (with the GWAS Catalog) reviewed 169 publications (2012–2022, across 157 traits).

What did we learn?​

⚡ PEG prediction methods are highly inconsistent
⚡ Evidence types and reporting standards vary widely
⚡ The field urgently needs a common PEG standard

What’s next?​

At ASHG 2025, we’re bringing a new PEG standard designed to make PEG data FAIR — Findable, Accessible, Interoperable, and Reusable.

📍 Save the date in Boston

• 🗓️ Ancillary Session: Oct 17 | 11:45 am – 1:15 pm | Room 259A
• 📌 Poster: Oct 16 | 2:30 pm – 4:30 pm | Exhibit & Poster Hall, Lower Level

👉 Join us to shape the future of effector gene prediction and PEG standards: Sign up here

Talks from the Knowledge Portal Network, Open Targets, GWAS Catalog, ClinGen, and others sparked ideas we are carrying forward.

We explored:

• 🔑 Different approaches to building PEG lists
• 🔑 Challenges in sharing, updating, and reusing them
• 🔑 First steps toward a community standard for reporting PEG data

👉 Missed it? Materials & recordings are available: Workshop Materials

Follow along as we count down to ASHG 2025, where we’ll share the outcomes through our poster and ancillary session.

📍 Save the date in Boston:

• 🗓️ Ancillary Session: Oct 17 | 11:45 am – 1:15 pm | Room 259A
• 📌 Poster: Oct 16 | 2:30 pm – 4:30 pm | Exhibit & Poster Hall, Lower Level

Join us to shape the future of effector gene prediction and PEG standards: Join Us